Agenda | ADDS Atlanta 2026

Event DaysFebruary 23-25
Kick OffFebruary 23
Day 1February 24
Day 2February 25

9:00 AM → 5:00 PM

KICK OFF - MONDAY, FEBRUARY 23

1:00 PM → 5:00 PM

Pre-Conference Workshop: Advancing Clinical Measurement in Huntington’s Disease with Wearable Digital Health Technology

Piedmont Ballroom

This workshop will examine the limitations of current endpoints in Huntington's disease (HD) clinical trial design, assess the evolving landscape and remaining gaps in digital measurement development, and incorporate regulatory perspectives on the use of passive digital health technologies.

Through multi-stakeholder discussion, participants will align on evidence-generation priorities, resulting in a structured gap mapping of key challenges and existing validation evidence, a shared framework to guide future evidence generation, and a call-to-action paper and/or the formation of a focused working group to drive next steps.

This session is designed for those committed to improving the rigor, relevance, and efficiency of HD clinical trials.

Session 1: The Current Measurement Tool in the Context of Clinical Trial Design
Session 2: Current Landscape of Digital Measurement Development
Session 3: Evidence Generation Plan

Michelle Campbell, PhD

FDA

Lori Quinn, PhD

Columbia University

Jamie Adams, MD

University of Rochester Medical Center

Jonas Dorn, PhD

Roche

Matthew Roche, PhD

CDHI Foundation

Swati Sathe, PhD

CDHI Foundation

Christine Guo, PhD

Ametris

6:00 PM → 8:00 PM

Welcome Reception

Piedmont Foyer

Please join us for the official ADDS 2026 welcome reception with refreshments and small bites. Early event check-in will be available until 8:00 PM.

9:00 AM → 5:00 PM

DAY 1 - TUESDAY, FEBRUARY 24

7:30 AM

Registration Opens

Piedmont Foyer

7:30 AM → 8:30 AM

Breakfast

Piedmont Ballroom

8:30 AM → 9:00 AM

Welcome and Opening Remarks

Grand Ballroom

Jeremy Wyatt

Ametris

9:00 AM → 5:00 PM

SESSION 1: PHYSICAL ACTIVITY AND MOBILITY

9:00 AM → 9:15 AM

One Step at a Time; the Winding Road to Measuring Physical Activity in Clinical Trials

Featured Speaker

Grand Ballroom

Carrie Northcott, PhD

Pfizer

9:15 AM → 9:30 AM

The Construct Validity of Real-World Digital Mobility Outcomes in People with Chronic Obstructive Pulmonary Disease: Results and a Digital Biomarker Validation Framework

Featured Speaker

Grand Ballroom

Dimitrios Megaritis, PhD

Northumbria University

9:30 AM → 9:45 AM

Utility of Digital Motor Score in Clinical Development in Neurology

Featured Speaker

Grand Ballroom

Jonas Dorn, PhD

Roche

9:45 AM → 10:00 AM

Digital Measures for Clinical Trial Endpoints in Huntington's Disease: the MEND-HD Study

Featured Speaker

Grand Ballroom

Lori Quinn, PhD

Columbia University

10:00 AM → 11:00 AM

Scientific Poster Session and Networking Break

Piedmont Foyer

11:05 AM → 11:35 AM

SESSION 2: SLEEP AND SCRATCH

11:00 AM → 11:15 AM

DECODE Nocturnal Scratch

Featured Speaker

Grand Ballroom

Matthew Patterson, PhD

Ametris

11:15 AM → 11:30 AM

At-Home Evaluation of Both Wearable and Touchless Digital Health Technologies for Measuring Nocturnal Scratching in Atopic Dermatitis

Featured Speaker

Grand Ballroom

Mark Morris

Johnson & Johnson Innovative Medicine

11:30 AM → 11:45 AM

Daytime Sleepiness and Challenges with Total Sleep Opportunity Identification

Featured Speaker

Grand Ballroom

Andy Liu, PhD

Ametris

11:05 AM → 11:35 AM

SESSION 3: PHARMA INNOVATION SHOWCASE

11:45 AM → 12:00 PM

Lilly's Digital Health Innovation Hub: Driving Integration of DHTs in Clinical Development

Featured Speaker

Grand Ballroom

Brian Winger, PhD

Eli Lilly and Company

12:00 PM → 12:15 PM

Accelerating Digital Health Innovation with China for Global Clinical Development

Featured Speaker

Grand Ballroom

Yue Wang, PhD

AstraZeneca China

12:15 PM → 12:30 PM

Wearable Innovation in Heart Failure: Toward Closing Unmet Needs

Featured Speaker

Grand Ballroom

Elias Abou Zeid, PhD

Novo Nordisk

12:30 PM → 1:45 PM

Networking Lunch

Piedmont Ballroom

1:00 PM → 4:45 PM

SESSION 4: REGULATORY

1:45 PM → 2:10 PM

Advancing Regulatory Science for Clinical Outcome Assessments: Applying Guidance to Develop Novel Digital Endpoints (tentative title)

Keynote Speaker

Grand Ballroom

Michelle Campbell, PhD

U.S. Food and Drug Administration (FDA)

2:10 PM → 2:25 PM

Regulatory Engagements as a Pre-Competitive Consortium: DECODE Perspective

Featured Speaker

Grand Ballroom

Sylvain Zorman, PhD

Ametris

2:25 PM → 2:40 PM

Why DECODE-Obesity: Qualitative Evidence Supports Sensor-based Outcomes for Physical Function

Featured Speaker

Grand Ballroom

Jay Trudeau, PhD

Eli Lilly and Company

2:40 PM → 2:55 PM

Finding Needles in a Haystack: Where we are with a Regulatory-Endorsed Digital Endpoint for ALS

Featured Speaker

Grand Ballroom

Collin Hovinga

Critical Path Institute (C-Path)

2:55 PM → 3:45 PM

Scientific Poster Session and Networking Break

Piedmont Foyer

3:45 PM → 4:35 PM

Panel Discussion: Regulatory

Panel Discussion

Grand Ballroom

4:35 PM → 5:05 PM

Selected Oral Presentations

Featured Speakers

Grand Ballroom

4:35 PM → 4:50 PM

Rationale for Digital Health Technology Assessments in FUNCtion ALS, a Phase 1/2 Trial of TRCN-1023, in Adult People Living with ALS

Sanjay Chandriani, PhD
Trace Neuroscience

4:50 PM → 5:05 PM

Targeting Naturalistic Movement with Adaptive Deep Brainstimulation in Parkinson’s Disease: a Randomized Feasibility Trial

Daryl Lawrence
UCSF

Sanjay Chandriani, PhD

Trace Neuroscience

Daryl Lawrence

UCSF

5:05 PM → 5:15 PM

Day 1 Wrap Up

Grand Ballroom

Jeremy Wyatt

Ametris

7:00 PM → 9:00 PM

Evening Cocktail Reception and Dinner

Grand Ballroom

9:00 AM → 5:00 PM

DAY 2 - WEDNESDAY, FEBRUARY 25

7:30 AM

Registration Opens

Piedmont Foyer

8:00 AM → 9:00 AM

Breakfast

Piedmont Ballroom

9:30 AM → 10:45 AM

SESSION 5: ARTIFICIAL INTELLIGENCE

9:00 AM → 9:15 AM

Building the Foundation: Shared, Pre-Competitive Foundation Model for Digital Endpoints in Drug Development

Featured Speaker

Grand Ballroom

Sheraz Khan, PhD

Pfizer

9:15 AM → 9:30 AM

Toward a Future of Increased Immunotherapy Access: The Potential of AI and High-Quality Digital Data

Featured Speakers

Grand Ballroom

Jonas Paludo, MD

Mayo Clinic

Michael Pettinati, PhD

Ametris

9:30 AM → 9:45 AM

Transforming Clinical Outcome Assessments with Machine Learning and Wearable Technology

Featured Speaker

Grand Ballroom

Kimberly Kontson, PhD

U.S. Food and Drug Administration (FDA)

9:45 AM → 10:00 AM

Foundation Model and Large Sensor Data for Personal Health

Featured Speaker

Grand Ballroom

Yuzhe Yang, PhD

UCLA

10:00 AM → 10:45 AM

Panel Discussion: Artificial Intelligence

Panel Discussion

Grand Ballroom

10:45 AM → 11:45 AM

Scientific Poster Session and Networking Break

Piedmont Foyer

10:45 AM → 11:15 AM

SESSION 6: METHODOLOGY

11:45 AM → 12:00 PM

Device Comparability and Data Compatibility Across ActiGraph Generations

Featured Speaker

Grand Ballroom

Samuel LaMunion, PhD

LaMunion Research Solutions & Consulting

12:00 PM → 12:15 PM

Does Rotation Matter? Use of a Gyroscope with an Accelerometer Sensor for Prediction of Sedentary Time and Physical Activity Type

Featured Speaker

Grand Ballroom

Scott Crouter, PhD

University Tennessee Knoxville

12:15 PM → 12:30 PM

Ametris Data Science and Platform Update

Featured Speaker

Grand Ballroom

Rakesh Pilkar, PhD

Ametris

12:30 PM → 12:45 PM

Strategies for Developing Digital Clinical Outcome Assessments Using Wearable Sensors in Pediatrics

Featured Speaker

Grand Ballroom

Catherine Lang, PT, PhD

Washington University School of Medicine

12:45 PM → 1:00 PM

Closing Remarks

Grand Ballroom

Christine Guo, PhD

Ametris

1:00 PM → 1:30 PM

ALS Pre-Conference Workshop

1:00 PM → 1:30 PM

Pathway to regulatory-accepted Digital Endpoint: Lessons Learned from Case Studies

Featured Speaker

ActiGraph Headquarter

Christine Guo, PhD

Chief Scientific Officer
ActiGraph

1:30 PM → 1:50 PM

What is the Endgame? Multistakeholder Perspectives for Clinicians, Industry, Regulators and Patients

Featured Speaker

ActiGraph Headquarter

Dr. Nadia Sethi

Co-Chair and Advocacy Committee
Northeast ALS Consortium Patient Education

1:50 PM → 2:50 PM

Current Level of Evidence

Roundtable Presentation

ActiGraph Headquarter

This roundtable session will focus on how we can accelerate the integration of actigraphy in ALS research. This session brings together experts to discuss the current level of evidence that exists for digital endpoints in ALS. Panelists will then discuss what near-term next steps are necessary to generate the evidence needed to validate these digital endpoints for use in clinical research and development. Participants will have the opportunity to engage in meaningful dialogue and contribute to shaping the future of ALS research.

Ruben van Eijk, MD

UMC Utrecht

Fernando Vieira, MD

ALS Therapy Development Institute

Cheryl Coon, PhD

Critical Path Institute

Frederik Steyn, PhD

University of Queensland

2:50 PM → 3:00 PM

Break

ActiGraph Headquarter

3:00 PM → 5:00 PM

Interactive Discussion

ActiGraph Headquarter

Gap Mapping: What we need to know?
Evidence Generation: How do we get there in the next 3-5 years?
Concluding discussion and formulation of action plan

6:00 PM → 8:00 PM

Welcome Reception

Emerald Coast Room

Please join us for the official ActiGraph Digital Data Summit 2025 kick off with refreshments and hors d'oeuvres. Early event check-in will be available till 8:00 PM.

7:30 AM

Registration Opens

Ballroom Foyer 1-2

7:30 AM → 8:30 AM

Breakfast

Ballroom Foyer 1-2

8:30 AM → 9:00 AM

Welcome and Opening Remarks

Ballroom A-F

Jeremy Wyatt

Chief Executive Officer
ActiGraph

9:00 AM → 5:00 PM

Physical Activity Focused Sessions

9:00 AM → 9:30 AM

The Pfizer Journey to Novel Digital Measures

Keynote Presentation

Ballroom A-F

Tim McCarthy, PhD

VP and Head of Biomeasures, Endpoints and Study Technologies
Pfizer

9:30 AM → 9:45 AM

What Actigraphy Can Tell us in Pulmonary Arterial Hypertension

Featured Speaker

Ballroom A-F

Daniel Lachant, DO

Assistant Professor of Medicine
University of Rochester Medical Center

9:45 AM → 10:00 AM

Leveraging Data Science to Optimize Digital Health Technology Deployments

Featured Speaker

Ballroom A-F

Daniel Sanchez

Associate Director, Oncology Data Science and Digital HealthResearch and Development
J&J Innovative Medicine

10:00 AM → 10:30 AM

Networking Break / Sponsor Exhibits

Ballroom Foyer 1-2

10:30 AM → 10:45 AM

Developing a Novel Digital Endpoint for Cancer Cachexia

Featured Speaker

Ballroom A-F

Lukas Adamowicz

Senior Data Scientist
Pfizer

10:45 AM → 11:05 AM

ActiGraph Science and Technology Roadmap

Featured Speakers

Ballroom A-F

Kim Rejndrup

Chief Product Officer
ActiGraph

Ali Neishabouri, PhD

Head of Data Science
ActiGraph

11:05 AM → 11:35 AM

AI in Digital Health Focused Sessions

11:05 AM → 11:15 AM

Adding Context to Measures: Self-supervised Learning for Human Activity Recognition

Featured Speaker

Ballroom A-F

Dawid Gerstel, PhD

Data Engineer
ActiGraph

11:15 AM → 11:25 AM

Evaluation Framework for Generative AI in Clinical Workflows

Featured Speaker

Ballroom A-F

Sheraz Khan, PhD

Director of Data Science
Pfizer

11:25 AM → 11:35 AM

Practical Considerations for AI in Oncology: Enhancing Clinical Trials and Patient Care

Featured Speaker

Ballroom A-F

Michael Pettinati, PhD

Senior Data Scientist
ActiGraph

11:35 AM → 1:00 PM

Lunch

White Sands Room

12:00 PM → 12:45 PM

Lunch and Learn Seminar - Modernizing Clinical Trials with ActiGraph Connect

Featured Speaker

Coral Reef Room

Kim Rejndrup

Chief Product Officer
ActiGraph

1:00 PM → 4:45 PM

ALS Mini-Symposium

1:00 PM → 1:15 PM

DigitALS Working Group: Systematic Review and Best Practice

Featured Speaker

Ballroom A-F

Emma Hodson-Tole, PhD

Professor of Neuromuscular Biomechanics
Manchester Metropolitan University

1:15 PM → 1:45 PM

ALS TDI Takeaway in Large-Scale Actigraphy Research

Keynote Presentation

Ballroom A-F

Fernando Vieira, MD

CEO and Chief Scientific Officer
ALS Therapy Development Institute

1:45 PM → 2:30 PM

Selected Talks

Ballroom A-F

Actigraphy in ALS Clinical Studies

Anil Tarachandani

Quantifying Short Prescribed Exercises Using Wearables Can Track Uppper Limb Function in ALS

Katherine Burke, PT, DPT and Marcin Straczkiewicz, PhD

Validating Wrist-Worn Accelerometry as a Practical and Scalable Tool for Continuous Monitoring in MND Clinical Trials

Cory Holdom

Anil Tarachandani

VP and Head of Translational Medicine
Verge Genomics

Katherine Burke, PT, DPT

Marcin Straczkiewicz, PhD

Cory J. Holdom

PhD Student

2:30 PM → 3:30 PM

Scientific Poster Session / Networking Break

Ballroom Foyer 1-2

3:30 PM → 3:45 PM

Patient-Centered Research for ALS Endpoint Development

Featured Speaker

Ballroom A-F

Cheryl Coon, PhD

Vice President, Clinical Outcome Assessment (COA) Program
Critical Path Institute (C-Path)

3:45 PM → 4:30 PM

ALS Pre-Conference Workshop Readout

Panel Discussion

Ballroom A-F

Christine Guo, PhD

Chief Scientific Officer
ActiGraph

4:30 PM → 4:45 PM

Day 1 Wrap Up

Ballroom A-F

Jeremy Wyatt

Chief Executive Officer
ActiGraph

7:00 PM → 9:00 PM

Evening Reception with Cocktails, Tapas, and DJ

Ballroom A-F

7:30 AM

Registration Opens

Ballroom Foyer 1-2

8:00 AM → 9:00 AM

Breakfast

Ballroom Foyer 1-2

9:00 AM → 9:40 AM

Regulatory Guidance on the Development of Novel Digital Endpoints

Keynote Panel Discussion

Ballroom A-F

Cheryl Coon, PhD

Critical Path Institute

Collin Hovinga

Critical Path Institute

Tim McCarthy, PhD

Pfizer

Fernando Vieira, MD

ALS Therapy Development Institute

9:00 AM → 12:15 PM

Cohort Studies Session

9:40 AM → 9:55 AM

NHATS: Considerations for Implementation in Large Cohort Studies

Featured Speaker

Ballroom A-F

Jennifer Schrack, PhD

Professor and Director, Center on Aging and Health
The Johns Hopkins University

9:55 AM → 10:10 AM

Leveraging the NHANES Cohort to Derive Reliable Clinical Endpoints from Continuous DHT Data

Featured Speaker

Ballroom A-F

Andy Liu, PhD

Biostatistician
ActiGraph

10:10 AM → 10:25 AM

UK Biobank: Device-Measured Movement Behaviours in Large-Scale, International Epidemiological Cohorts

Featured Speaker

Ballroom A-F

Laura Brocklebank, PhD

University of Oxford

10:25 AM → 10:55 AM

Networking Break / Sponsor Exhibits

Ballroom Foyer 1-2

10:45 AM → 12:45 PM

Multi-Stakeholder Collaboration Session

10:55 AM → 11:25 AM

Stepping into the Real World with Mobilise-D

Keynote Presentation

Ballroom A-F

Brian Caulfield, PhD

Professor of Physiology, PI and Founding Director, INSIGHT Centre for Data Analytics
University College Dublin

11:25 AM → 12:05 PM

Digital Endpoint Collaboration to accelerate Outcome DEvelopment (DECODE)

Panel Discussion

Ballroom A-F

Sylvain Zorman, PhD

Director Digital Health Sciences
ActiGraph

12:05 PM → 12:20 PM

Development of Wearable-Derived Digital Endpoint for Neuromuscular Diseases

Featured Speakers

Ballroom A-F

Tina Duong PT, PhD

Physical Therapist, Sr. Research Scientist, Director or Clinical Outcomes Research and Development
Stanford UniversityDivision of Neuromuscular Medicine

Rakesh Pilkar, PhD

Senior Data Scientist
ActiGraph

12:20 PM → 12:40 PM

Validation of PPG Technology for Vital Sign Monitoring

Featured Speakers

Ballroom A-F

Mathieu Lemay, PhD

Signal Processing and AI Group
CSEM

Matthew Patterson, PhD

Senior Data Scientist
ActiGraph

12:40 PM → 12:45 PM

Closing Remarks

Ballroom A-F

Christine Guo, PhD

Chief Scientific Officer
ActiGraph

1:00 PM → 4:00 PM

Excursion - Trolley to ActiGraph Headquarters Tour

Lunch and Guided Tour

ActiGraph Headquarter

Meet in hotel lobby to board trolley

February 26, 2024 Day 1

Emerald Coast Room

February 27, 2024 Day 2

Ballroom Foyer 1-2

Ballroom A-F